Which type of cells can differentiate into two or more lineages?

The correct choice is that pluripotent cells can differentiate into two or more lineages. Pluripotent cells, such as embryonic stem cells, have the remarkable ability to develop into virtually any cell type in the body, except for extra embryonic tissues. This extensive differentiation potential allows them to give rise to the three primary germ layers: endoderm, mesoderm, and ectoderm, which in turn can form a diverse range of tissues and organs.

Unipotent cells, on the other hand, can only differentiate into one specific cell type, representing a more limited potential than pluripotent cells. Multipotent cells can differentiate into a limited range of cell types usually related to a specific tissue or organ, but not into any cell type, which is a hallmark of pluripotent cells. Oligopotent cells have the ability to differentiate into a few closely related cell types, which again limits their potential compared to pluripotent cells.

Thus, the defining feature of pluripotent cells is their capacity to give rise to multiple lineages, making them critical in developmental biology and regenerative medicine.