Which type of cell is typically in the G0 phase for the lifetime of an individual?

Cells in the G0 phase are considered to be in a quiescent state, which means they are not actively dividing but can remain metabolically active for various functions. Cardiomyocytes and neurons are two cell types that typically remain in the G0 phase for the lifetime of an individual.

Cardiomyocytes, the heart muscle cells, are known for their limited ability to proliferate after birth. They enter into a terminally differentiated state in which they do not typically re-enter the cell cycle, making them primarily responsible for maintaining the function of the heart rather than undergoing cell division.

Neurons, on the other hand, also enter the G0 phase after development. Once fully differentiated, most neurons do not undergo mitosis. They have a crucial role in transmitting signals throughout the nervous system; however, once they are matured, they typically remain in a post-mitotic state for the lifetime of the organism.

Bone marrow cells, particularly hematopoietic stem cells, are not in the G0 phase for their entire lifespan. These stem cells are capable of dividing and giving rise to various blood cell lineages throughout life. Their role involves regular proliferation to support continuous blood cell production, especially in response to physiological demands.

Thus, both cardiomy