Which scaffold fabrication technique is NOT typically used?

Radiation as a scaffold fabrication technique is not typically employed in tissue engineering. This is primarily because the techniques commonly used for scaffold fabrication focus on creating porous structures that can support cell migration, nutrient flow, and tissue integration.

In solvent casting and particulate leaching, a polymer solution is cast and then leached to create a porous structure. Gas foaming involves the generation of gas bubbles in the polymer matrix to form pores, which is beneficial for enhancing permeability and mimicking natural tissue structures. Phase separation is a technique used to create porous scaffolds by separating phases in a polymer solution, which also results in desirable porosity and architecture for tissue support.

While radiation may have applications in sterilization or crosslinking materials for scaffolds, it is not a primary method for creating the actual scaffold structure compared to the other techniques listed. Understanding the specific purposes and applications of each technique helps clarify why radiation is less relevant in the context of scaffold fabrication.