Which properties are NOT shared between natural polymers and the ECM?

Natural polymers and the extracellular matrix (ECM) share several key properties that make them both favorable choices in tissue engineering applications. Gelation ability, biodegradability, and water binding capacity are significant characteristics that contribute to their functionality, compatibility with biological systems, and support in tissue formation.

When it comes to gelation ability, both natural polymers and the ECM can form hydrogels, allowing for a suitable environment for cellular activities. Biodegradability is another vital attribute, as it ensures that the materials can be safely and effectively broken down and replaced by natural tissues over time. Water binding capacity is crucial as well; both natural polymers and the ECM can retain water, which supports cell hydration and nutrient transport.

On the other hand, the aspect of cheap production is not uniformly shared. While some natural polymers can be produced at low costs, the ECM is a complex structure that can be more expensive to isolate or replicate. The costs associated with sourcing or synthesizing materials that mimic ECM properties can vary widely, making it less predictable in terms of affordability compared to natural polymers. Thus, the production cost is not consistently low across both categories. Understanding this distinction highlights the economic considerations that influence material choices in tissue engineering.