Which of the following is not true about scaffolds?

Scaffolds in tissue engineering are designed to serve as a temporary framework that supports the growth and organization of cells as they develop into a tissue. They are not intended to be permanent structures; instead, they typically degrade over time as the new tissue forms and takes over the scaffolding function. This degradation is crucial as it allows for natural tissue integration and remodeling, ultimately leading to a functional tissue that is independent of the scaffold.

The other options highlight essential characteristics of scaffolds. Scaffolds can indeed be made from natural or synthetic materials, which provides versatility in their design and application. Porosity is also a critical attribute, as it enhances nutrient and waste exchange, supports cell infiltration, and aids in vascularization within the developing tissue. These features are vital for promoting cellular behaviors that lead to successful tissue regeneration.