Which of the following is NOT a requirement for tissue engineering scaffolds?

The choice of "environmentally responsive" as a requirement for tissue engineering scaffolds is not essential compared to the other factors listed. For scaffolds in tissue engineering, the primary goals include providing structural support, enabling cell attachment, and facilitating tissue development.

Optimum porosity is crucial because it allows for nutrient and waste exchange, necessary for cell survival and function within the scaffold. A suitable surface chemistry is important as it influences cell adhesion, proliferation, and differentiation, which are key processes in tissue formation. An interconnected pore network is vital for promoting vascularization and ensuring that cells can migrate throughout the scaffold, enhancing overall tissue integration and functionality.

While being environmentally responsive could enhance performance under specific conditions, it is not a fundamental requirement for all tissue engineering applications, unlike the other choices that serve as basic criteria for effective scaffold design.