Which of the following is NOT a common use for Calcium Hydroxyapatite (HA)?

Calcium Hydroxyapatite (HA) is a widely used biomaterial in tissue engineering and regenerative medicine, particularly due to its biocompatibility and osteoconductive properties. The assertion that HA is not commonly used as a bone filler in high load-bearing applications is accurate, primarily because high load-bearing areas require materials that possess not only biocompatibility but also the mechanical strength and durability to withstand significant forces over time.

HA is typically utilized in applications that require lower mechanical loads, as it may not provide the necessary strength and stability when subjected to high stresses. Common applications for HA include coatings for metallic implants to enhance osseointegration, as well as use in the repair of periodontal defects and as a filler in non-load bearing applications where its properties can contribute to bone regeneration without the need for high mechanical performance.

By focusing on the nature of load-bearing versus non-load-bearing applications, one can see why Calcium Hydroxyapatite is not ideal in high load situations, reinforcing its suitability for more specific contexts in tissue engineering.