Which of the following are requirements for a successful cell cycle?

A successful cell cycle is fundamental to proper cell division and overall tissue function. Each of the requirements listed plays a crucial role in ensuring that the cycle proceeds effectively and in a regulated manner.

The sequence of phases in the cell cycle is critical, specifically the fact that the S phase, where DNA replication occurs, must precede the M phase, during which mitosis and cell division take place. This sequential order is vital to ensure that each daughter cell receives the correct amount of genetic material.

Responsiveness to checkpoint controls is another essential requirement, as these checkpoints monitor the integrity of the cell's DNA and the proper completion of the preceding phases before allowing the cell cycle to proceed. This mechanism prevents cells from dividing inappropriately, which can lead to genomic instability and diseases, such as cancer.

Balanced growth and division refer to the need for a cell to grow adequately and replicate its components to ensure that both daughter cells achieve the necessary size and cellular function. If growth or division becomes unbalanced, it can result in various physiological issues, impacting the tissue's overall health.

All of these elements are interrelated and essential for the proper progression and regulation of the cell cycle, which is why selecting the option that encompasses all of them is the most comprehensive choice.