Which is a physiological condition of annulus fibrosus tissue?

The physiological conditions of annulus fibrosus tissue are pivotal for understanding its mechanical characteristics and functional roles within the intervertebral disc. The annulus fibrosus, comprised of layers of collagen fibers, is designed to withstand various types of mechanical stress while maintaining the structural integrity of the disc.

Physiologically-relevant strain being around 6% is significant because it reflects the typical deformation the annulus is subjected to during the normal range of motion and loading conditions in the spine. This strain level is essential for maintaining the health of the tissue and ensuring that its mechanical properties are suitable for its role in load distribution and support.

The compressive stress of 300 MPa represents a typical loading condition experienced by the annulus fibrosus under physiological circumstances. This level of stress highlights the annulus's ability to bear substantial loads, essential for its function in weight support and movement.

The range of physiologically-relevant frequency, particularly around 0.1-1 Hz, is indicative of the natural loading frequencies experienced by the tissue during typical activities such as walking or running. These frequencies are important as they can affect the tissue's response to mechanical loading and its overall health.

Given that all the listed factors—strain, compressive stress, and