Which growth factor is responsible for recruiting tendon progenitor cells and stimulating collagen production?

Study for the Tissue Engineering Exam. Enhance your knowledge with flashcards and multiple choice questions, each with hints and explanations. Prepare effectively for your assessment!

The growth factor that plays a crucial role in recruiting tendon progenitor cells and stimulating collagen production is PDGF (Platelet-Derived Growth Factor). PDGF is significant in the healing and regenerative processes, particularly for connective tissues such as tendons. It acts as a chemotactic agent, attracting progenitor cells to the site of injury or tissue repair. Once these cells are recruited, PDGF promotes their proliferation and enhances the synthesis of extracellular matrix components, including collagen, which is essential for tissue strength and integrity.

This activity is particularly important in tendon healing, where collagen is a primary structural protein. By supporting both cell recruitment and collagen production, PDGF helps facilitate the repair and regeneration of tendon tissue, making it a pivotal factor in tendon tissue engineering and regeneration strategies.

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