What stage of growth in Mesenchymal Stem cells (MSC) is after proliferation?

Study for the Tissue Engineering Exam. Enhance your knowledge with flashcards and multiple choice questions, each with hints and explanations. Prepare effectively for your assessment!

The stage of growth in Mesenchymal Stem Cells (MSC) that follows proliferation is commitment. During the commitment stage, MSCs undergo a series of changes that prepare them for differentiation into specific cell lineages. This process is characterized by the cells becoming more restricted in their potential, aligning themselves with specific pathways that lead to a particular type of tissue or cell type, such as bone, cartilage, or fat.

This stage is crucial as it sets the foundation for the subsequent differentiation phase where MSCs will actually start the process of maturing into specialized cells. Commitment is essentially the precursor to differentiation, marking a point where the stem cells have made a choice regarding their future development, but have not yet fully committed to becoming a differentiated cell type.

Differentiation, which typically follows commitment, involves the actual transformation of the MSCs into mature cells with specific functions. Lineage progression and maturation would pertain to the later stages of development and specification that occur after commitment.

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