What is the primary function of a scaffold in tissue engineering?

The primary function of a scaffold in tissue engineering is to support cell attachment and growth. Scaffolds serve as a three-dimensional structure that mimics the extracellular matrix, providing a conducive environment for cells to adhere, proliferate, and differentiate into the desired tissue type. This support facilitates the organization of cells into functional tissues and is essential for the development and regeneration of organs.

While scaffolds can play a role in nutrient diffusion and may affect the immune response and stability of the engineered tissue, their central role is fundamentally tied to creating a physical platform that encourages cells to attach and establish themselves within the scaffold. This ability to guide cell behavior is critical for successful tissue engineering applications, making the support of cell attachment and growth the primary focus of scaffold design.