What is the most common strategy used in tissue engineering?

The most common strategy used in tissue engineering is the placement of cells on or within matrices. This approach is fundamental because it leverages the use of scaffolding materials that provide structural support for cells as they grow and differentiate into functional tissue. Matrices can be made from natural or synthetic materials and are designed to mimic the extracellular matrix found in human tissues, facilitating cellular attachment, proliferation, and differentiation.

Using matrices allows for better control of the tissue microenvironment, which is crucial for successful tissue regeneration. Cells interact with the scaffold, which can be engineered with specific biochemical and mechanical properties to enhance cellular behavior and promote the formation of new tissue.

This strategy has been effective in various applications, such as skin, cartilage, and bone regeneration, by creating a conducive environment for cells to thrive and form complex, functional tissues. Other strategies, like infusion of cells or substances, may complement this approach but do not typically serve as the primary method of tissue construction and integration.