What is the main purpose of scaffolds in tissue engineering?

The main purpose of scaffolds in tissue engineering is to serve as a framework for new tissue growth. Scaffolds provide a supportive structure that mimics the extracellular matrix, which is crucial for cell attachment, proliferation, and differentiation. When cells are seeded onto these scaffolds, they can migrate and populate the material, eventually leading to the formation of new tissue. The physical properties of the scaffold, such as porosity and mechanical strength, can influence cell behaviors and the overall development of functional tissue.

While scaffolds may indirectly contribute to nutrient delivery and could be designed to incorporate drug delivery systems or electrical stimuli, their primary function is truly centered around the structural support required for tissue regeneration.