The pore size used for most bone ingrowth settings is between:

The appropriate pore size for bone ingrowth is critically important for ensuring adequate biological response and effective integration of scaffolds with native bone. A pore size between 150 and 500 μm is widely recognized as being optimal for promoting bone ingrowth. This size range supports the infiltration of cells, facilitates the transport of nutrients and waste, and encourages angiogenesis, which are all vital for bone regeneration and healing.

Pores that are too small may impede cell migration and nutrient flow, while those that are too large can reduce the structural integrity of the scaffold, leading to compromised mechanical support. Specifically, the range of 150 to 500 μm provides a balanced environment conducive to osteoblast activity, necessary for new bone formation and successful incorporation into the biological environment. This established range is supported by numerous studies in the tissue engineering literature, which demonstrate that scaffolds with these pore sizes yield the best outcomes in terms of bone tissue formation and scaffold performance.