For osteoporosis treatment, what effect can Nitroglycerin have?

Nitroglycerin, primarily known for its use as a vasodilator in treating angina and heart-related conditions, can indeed cause persistent headaches as a common side effect. This occurs because nitroglycerin works by relaxing the smooth muscles and dilating blood vessels, which can lead to increased blood flow to the brain and trigger headache responses in some patients.

While the other options mention a range of serious side effects or conditions, they do not directly relate to the known pharmacological effects or adverse reactions associated with nitroglycerin. Persistent headaches are well-documented in patients using nitroglycerin, making this the most accurate and relevant effect in the context of treatment for osteoporosis, where vasodilation can be beneficial for bone health by improving blood flow.